Heading into the July 4 long weekend, President Donald Trump shared a late-night social media post slamming some his biggest celebrity critics as suffering from the imaginary “Trump Derangement Syndrome.”
In an AI video posted on Trump’s Truth Social account just before midnight Wednesday, the president is dressed as “Dr. Trump” and, in the soothing tones of a pharmaceutical ad, he claims to “have a treatment plan” for those suffering from “Trump Derangement Syndrome.” The clip then presents fake testimonials from Rosie O’Donnell, “The View” co-host Whoopi Goldberg and Robert De Niro who describe their “TDS” symptoms. Also featured as purported TDS suffers are AI-generated versions of Julia Roberts, John Leguizamo and Edward Norton.
Trump appears to believe that “TDS” is a real medical condition, saying at a May event at the White House that “I’m hearing it is actually a disease” (via Mediaite).
After Rob Reiner and his wife Michele were murdered last December, Trump wrote in a post on Truth Social that the director and actor had died “reportedly due to the anger he caused others through his massive, unyielding, and incurable affliction with a mind crippling disease known as TRUMP DERANGEMENT SYNDROME, sometimes referred to as TDS.”
In the fake “Dr. Trump” video, an AI-generated O’Donnell says, “I have been suffering for over a decade and after listening to Dr. Trump, I can see some results.” The fake De Niro says, “I had no idea how much this was affecting my life. My work has slowed down. I’m hardly recognisable anymore. I just needed help. I couldn’t eat. I couldn’t sleep. Constantly angry. I made everyone miserable around me.”
Roberts’ AI avatar says in the video, “I feel like I’ve aged 20 years in the last two years” and says she had begun to “worry about her future.”
What is the cure for TDS? Here’s what Dr. Trump says in the video’s kicker: “Turn off fake news. Say your prayers and, if you ever feel anxious, just have a Diet Coke like me and you’re gonna see a remarkable difference in your life.”
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Trump routinely posts AI-generated images and videos. That included one this spring showing him as a Christ-like figure healing a sick man — a post that was subsequently deleted — which Trump told reporters he thought depicted him as a doctor:
Trump’s social account also has shared an AI image of himself dressed as the Pope and one depicting himself as Superman and other associates as DC superheroes. In October 2025, the president shared a video showing him Trump as a king in a fighter jet dropping a huge payload of feces on “No Kings” protesters in New York City.
And this February, Trump posted an AI video that portrayed Barack and Michelle Obama as apes, excerpted from a “Lion King”-themed meme. After the White House initially defended the post as satire, the video in question was deleted after a backlash including from some Republicans. Trump did not apologize for posting the racist video, telling reporters, “I liked the beginning. I saw it and just passed it on, and I guess probably nobody reviewed the end of it.”
Watch the fake “Dr. Trump” video:
From Variety US